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Mouse Epidermal Growth Factor Receptor 2 (EGFR2) ELISA Kit-Sandwich

Cat. No.EK5F502

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Epidermal Growth Factor Receptor 2 (EGFR2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse EGFR2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Epidermal Growth Factor Receptor 2 (EGFR2).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

In mice, Epidermal Growth Factor Receptor 2 (EGFR) primarily facilitates cell proliferation, differentiation, migration, and signal transduction. During the branching morphogenesis of the mouse fetal mandibular gland (SMG), EGF initiates signaling pathways like ERK-1/2 and PI3K via EGFR2, thus managing cell proliferation and differentiation. EGFR2 also exhibits anti-apoptotic properties in mouse hepatocytes. Research indicates that EGF can shield hepatocytes from apoptosis by activating EGFR2's tyrosine kinase activity. In the trophoblast cells of mouse embryos, EGF induces the secretion of hCG and human placental lactogen (hPL), both crucial for embryonic development.

Target/Biomarker Mouse EGFR2
Target Synonym CD340; ErbB2; HER-2/neu; HER2; NEU; MLN 19; NGL; TKR1; p185; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2; Neuro/Glioblastoma Derived Oncogene Homolog

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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