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Mouse Eosinophil Chemotactic Factor (ECF) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Eosinophil Chemotactic Factor (ECF) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ECF in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Initially, ECF was thought to be a chemokine linked to human basophils and mast cells, but later research revealed that it can also be released from mouse eosinophils and exhibits high specificity for eosinophils. Mouse eosinophils stimulated by the calcium ionophore A23187 can release ECF in a time- and dose-dependent manner. Moreover, ECF is expressed at elevated levels in mouse eosinophils, particularly in tissues such as the lungs, spleen, and bone marrow. In mouse models, ECF is associated with a variety of pathological conditions. For instance, in a mouse model of allergic asthma, ECF-L (a form of ECF in mice) is produced by T lymphocytes and plays a crucial role in the development of airway hyperresponsiveness (AHR).
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.