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Mouse Eosinophil Cationic Protein (ECP) ELISA Kit-Sandwich

Cat. No.EK5F57

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Eosinophil Cationic Protein (ECP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ECP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Eosinophil Cationic Protein (ECP).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Eosinophil cationic protein (ECP), also known as ribonuclease 3, is a basic protein found in the primary matrix of eosinophils and is released during their degranulation. ECP is associated with inflammation and asthma, as its levels are elevated in these conditions. Studies have shown that eosinophils release mitochondrial DNA coated with ECP and other granule proteins, which have bactericidal effects in mice in vivo. Eosinophil cationic proteins are shown to have toxic effects on tracheal epithelium in guinea pigs.

Target/Biomarker Mouse ECP
Target Synonym Ribonuclease 3; RNase 3
UniProt ID P12724

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Bystrom, Jonas, Kawa Amin, and David Bishop-Bailey. "Analysing the eosinophil cationic protein-a clue to the function of the eosinophil granulocyte." Respiratory research 12 (2011): 1-20.
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