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Mouse Enhancer of Zeste Homolog 1 (EZH1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Enhancer of Zeste Homolog 1 (EZH1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse EZH1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Histone-lysine N-methyltransferase EZH1 is a polycomb group (PcG) protein that serves as the catalytic subunit of the PRC2/EED-EZH1 complex. This complex methylates 'Lys-27' of histone H3, resulting in the transcriptional repression of target genes. In mice lacking Ezh2, Ezh1 can partially fulfill the role of Ezh2, sustaining the function of hematopoietic stem cells. Additionally, Ezh1 helps preserve the developmental potential and anti-aging characteristics of hematopoietic stem cells by targeting bivalent genes. The absence of Ezh1 leads to reduced social behavior and increased motivational behavior in mice, potentially due to altered gene expression during neuronal maturation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Kaito, Satoshi, and Atsushi Iwama. "Pathogenic Impacts of Dysregulated Polycomb Repressive Complex Function in Hematological Malignancies." International journal of molecular sciences vol. 22,1 74. 23 Dec. 2020.