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Mouse Endosulfine Alpha (ENSa) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Endosulfine Alpha (ENSa) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ENSa in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Alpha-endosulfine is a protein phosphatase inhibitor that specifically targets protein phosphatase 2A (PP2A) during mitosis. Phosphorylated at Ser-67 during mitosis, it selectively binds to PPP2R2D (PR55-delta) and inhibits its activity, leading to PP2A inactivation. This is crucial for maintaining high cyclin-B1-CDK1 activity during the M phase. In mice, Alpha-endosulfine (ENSA) primarily regulates cell division and meiosis, playing a significant role in the meiotic maturation of oocytes. ENSA governs the transition of oocytes from the first meiotic prophase (prophase I) to the second meiotic phase (M-phase) by inhibiting PP2A activity. This regulatory process ensures the proper progression of meiosis and prevents aneuploidy.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.