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Mouse E1A Binding Protein P300 (EP300) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse E1A Binding Protein P300 (EP300) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse EP300 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The enzyme p300, a histone acetyltransferase, facilitates transcription regulation by modifying chromatin structure. It acetylates all four core nucleosomal histones. In mice, EP300 is crucial for regulating gene expression and is linked to various biological processes and conditions, including neurodegenerative diseases, tumor development, metabolic regulation, fibrotic diseases, acute liver damage, and the hematopoietic system. EP300 is vital for limb development in mice, where its deficiency may result in limb deformities and hearing impairment. Additionally, EP300 has a role in controlling gene expression at enhancer regions important for limb development.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.