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Mouse DNA Methyltransferase 3A (DNMT3A) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse DNA Methyltransferase 3A (DNMT3A) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DNMT3A in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
DNA (cytosine-5)-methyltransferase 3A is crucial for genome-wide de novo methylation and is essential for establishing DNA methylation patterns during development. This process is coordinated with histone methylation. Dnmt3a plays a pivotal role in mouse neural development, particularly in the proliferation and differentiation of neural stem cells. Research indicates that the absence of Dnmt3a leads to abnormal neural stem cell differentiation, decreasing the number of oligodendrocytes and neurons while increasing the proportion of astrocytes. Additionally, Dnmt3a is involved in neural regeneration during adulthood. For instance, inhibiting Dnmt3a in the axon regeneration of retinal ganglion cells can enhance axon regeneration and restore visual function.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.