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Mouse Dihydropyrimidinase Like Protein 2 (DPYSL2) ELISA Kit-Sandwich

Cat. No.EK6F641

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Dihydropyrimidinase Like Protein 2 (DPYSL2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DPYSL2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Dihydropyrimidinase Like Protein 2 (DPYSL2).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Dihydropyrimidinase-related protein 2 is involved in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse, and cell migration. It is essential for signaling by class 3 semaphorins and the subsequent remodeling of the cytoskeleton, and it may also play a role in endocytosis. DPYSL2, also known as CRMP2, is a crucial protein in the central nervous system, significantly contributing to axon growth, synapse formation, and neural development. Mutations or loss of function in the DPYSL2 gene are linked to various neurodevelopmental disorders. For instance, the absence of DPYSL2 in mice leads to autism spectrum disorder (ASD)-like phenotypes, such as defective neuronal pruning and insufficient synaptic elimination in the granule cells of the dentate gyrus.

Target/Biomarker Mouse DPYSL2
Target Synonym CRMP2; DHPRP2; DRP-2; DRP2; ULIP2; Unc-33-like phosphoprotein 2; Collapsin response mediator protein 2
Gene ID 12934
UniProt ID O08553

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Desprez, Florence et al. "Contribution of the dihydropyrimidinase-like proteins family in synaptic physiology and in neurodevelopmental disorders." Frontiers in neuroscience vol. 17 1154446. 17 Apr. 2023.
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