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Mouse Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1) ELISA Kit-Sandwich

Cat. No.EK6F294

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DGAT1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Diacylglycerol-O-Acyltransferase Homolog 1 (DGAT1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Diacylglycerol O-acyltransferase 1 (DGAT1) catalyzes the final and only committed step in triacylglycerol synthesis, utilizing diacylglycerol and fatty acyl CoA as substrates. It is predominantly expressed in the epithelial cells of the small intestine, where its activity is crucial for the absorption of dietary fats. In mice, DGAT1 is highly expressed in adipose tissue, and its deletion (DGAT1-/-) results in a significant reduction in triglyceride levels in adipose tissue, conferring resistance to diet-induced obesity and hyperlipidemia. DGAT1-/- mice maintain metabolic balance by increasing energy expenditure and enhancing insulin sensitivity.

Target/Biomarker Mouse DGAT1
Target Synonym ARGP1; DGAT; ARAT; ACAT-related gene product 1; Acyl-CoA retinol O-fatty-acyltransferase; Diglyceride acyltransferase
Gene ID 13350
UniProt ID Q9Z2A7

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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