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Mouse Deoxyribonuclease I Like Protein 3 (DNASE1L3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Deoxyribonuclease I Like Protein 3 (DNASE1L3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DNASE1L3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Deoxyribonuclease I-like 3, also known as Deoxyribonuclease gamma, is a highly efficient endonuclease capable of degrading extracellular free DNA (ecDNA) and chromatin. Research has demonstrated that DNASE1L3 can effectively cleave double-stranded DNA and chromatin through its distinctive C-terminal structure, a function essential to its role in the immune system. In mice, the absence of DNASE1L3 results in an abnormal length distribution of ecDNA in plasma, characterized by an increased proportion of longer DNA fragments, which may be linked to immune system activation and the development of autoimmune diseases.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.