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Mouse Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) ELISA Kit-Sandwich

Cat. No.EK6F353

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CYR61 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61).
Target Species Mouse
Species Reactivity Mouse
Detection Range 6.25-400 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

CCN family member 1, also known as Protein CYR61, is involved in promoting cell proliferation, chemotaxis, angiogenesis, and cell adhesion. It appears to contribute to wound healing by up-regulating genes related to angiogenesis, inflammation, and matrix remodeling in skin fibroblasts, such as VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1, and integrins alpha-3 and alpha-5. In mice, CCN1 performs various functions, including roles in angiogenesis, tissue repair, inflammatory response, heart disease, and tumorigenesis. In non-alcoholic fatty liver disease (NAFLD), CCN1 exacerbates liver inflammation and damage by recruiting macrophages and activating the MyD88-dependent signaling pathway.

Target/Biomarker Mouse CYR61
Target Synonym CCN1; GIG1; IGFBP10; CCN family member 1; Insulin-like growth factor-binding protein 10
Gene ID 16007
UniProt ID P18406

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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