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Mouse Cyclin Dependent Kinase 5 (CDK5) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Cyclin Dependent Kinase 5 (CDK5) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CDK5 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine-protein kinase crucial for neuronal cell cycle arrest and differentiation. It may play a role in apoptotic cell death in neurodegenerative diseases by inducing abortive cell cycle re-entry. Mice lacking Cdk5 exhibit severe structural abnormalities in the cerebral cortex, such as an inversion of the six cortical layers. Typically, medial neurons migrate first, followed by lateral neurons; however, in Cdk5-deficient mice, lateral neurons reach the cortical surface prematurely. Additionally, the absence of Cdk5 leads to disorganized stratification of the cerebral cortex, including abnormal separation of the preplate and the subplate.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.