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Mouse Crystallin Beta B2 (CRYbB2) ELISA Kit-Sandwich

Cat. No.EK6F544

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Crystallin Beta B2 (CRYbB2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CRYbB2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Crystallin Beta B2 (CRYbB2).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Crystallins are the key structural components of the vertebrate eye lens. βB2-crystallin is among the most abundant proteins in the mammalian lens, playing a crucial role in maintaining its transparency and refractive index. In mice, βB2-crystallin expression increases rapidly after birth, peaking in the lens cortex. Mutations or dysfunctions in βB2-crystallin can result in lens opacities and age-related cataracts. Additionally, βB2-crystallin contributes to the survival and neuroprotection of retinal ganglion cells, enhancing optic nerve function in a glaucoma model by reducing ganglion cell apoptosis.

Target/Biomarker Mouse CRYbB2
Target Synonym CCA2; CRYB2; CRYB2A; Beta-crystallin Bp
Gene ID 12961
UniProt ID P62696

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Anders, Fabian et al. "Intravitreal injection of β-crystallin B2 improves retinal ganglion cell survival in an experimental animal model of glaucoma." PloS one vol. 12,4 e0175451. 6 Apr. 2017.
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