Mouse Cross Linked C-Telopeptide of Type I Collagen (CTXI) ELISA Kit-Competitive

Cross Linked C-Telopeptide of Type I Collagen (ICTX) is a sensitive marker for bone resorption, with elevated levels typically indicating increased bone resorption rates. In mouse models, changes in ICTX levels can be utilized to investigate the onset and progression of bone metabolic diseases. For instance, in a fibrotic liver disease model, increased ICTX levels signify decreased stability of the collagen network, potentially linked to bone metabolic disorders. Additionally, ICTX may participate in other biological processes, such as immune response and inflammation. Research has demonstrated that ICTX interacts with immune-related molecules like fibronectin and discoidin domain receptors, possibly influencing bone metabolism indirectly by impacting immune cell function.