Products

Get a quote

We're excited to learn more about your project and provide you with a customized quote tailored to your needs. Please fill out the form below, and we'll get back to you as soon as possible.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Mouse Corticosteroid Binding Globulin (CBG) ELISA Kit-Sandwich

Name: Mouse Corticosteroid Binding Globulin (CBG) ELISA Kit-Sandwich
SKU: EK5F642
Rating: 5 (1 reviews)

Cat. No.EK5F642

Product TypeAnimal Immunoassay Kits

Size

Inquiry Now Add to Basket

Product Overview

BioVenic Mouse Corticosteroid Binding Globulin (CBG) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CBG in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Corticosteroid Binding Globulin (CBG).

Target Species Mouse

Species Reactivity Mouse

Detection Range 0.8-50 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Corticosteroid-binding globulin (CBG) is a primary transport protein for glucocorticoids and progestins in the blood across nearly all vertebrate species. In mice, CBG's function extends beyond regulating the free concentration of cortisol, playing roles in HPA axis signaling, stress response, adrenal function, and potentially metabolic regulation. Mice lacking CBG display abnormalities in HPA axis function, including elevated levels of corticotropin-releasing hormone (CRH) in the hypothalamus and altered secretion of adrenocortical hormones. Additionally, CBG deficiency leads to changes in cortisol activity within the hippocampus, which may impact cognitive function.

Target/Biomarker Mouse CBG

Target Synonym SERPINA6; Transcortin; Serpin A6; Serpin Peptidase Inhibitor;Clade A;Member 6(Alpha-1 Antiproteinase; Antitrypsin)

Gene ID 12401

UniProt ID Q06770

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Gulfo, José et al. "Corticosteroid-binding-globulin (CBG)-deficient mice show high pY216-GSK3β and phosphorylated-Tau levels in the hippocampus." PloS one vol. 16,2 e0246930. 16 Feb. 2021.