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Mouse Complement C3 Convertase (C3c) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Complement C3 Convertase (C3c) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse C3c in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In mice, the primary function of Complement C3 Convertase is to activate the complement system, which plays a crucial role in the immune response. The complement system is vital for immune surveillance and the maintenance of homeostasis, with C3 convertase being a core component. This key enzyme in the complement activation process catalyzes the cleavage of C3 into C3a and C3b. The C3b product is essential as it binds to the surface of antigens or pathogens, forming immune complexes that enhance phagocytosis and trigger inflammatory responses. C3 convertase operates in both the classical and alternative pathways of the complement system: it is composed of C4b2a in the classical pathway and of C3bBb in the alternative pathway.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Okroj, Marcin et al. "Functional analyses of complement convertases using C3 and C5-depleted sera." PloS one vol. 7,10 (2012): e47245.