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Mouse Collagen Type VII (COL7) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Collagen Type VII (COL7) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse COL7 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Type VII collagen is a lengthy collagen chain characterized by a central triple-helical region and two non-collagenous areas (NC-1 and NC-2). This distinct structure allows it to interact with various components within the epidermal basement membrane zone, including integrins and extracellular matrix proteins, thereby facilitating the formation of anchoring fibers. In mouse models, lacking type VII collagen or having functional defects can result in significant skin lesions. For instance, in a recessive hereditary mouse model of dystrophic epidermolysis bullosa (DEB), mutations in the type VII collagen gene (COL7A1) cause the loss of anchoring fibers, which leads to extensive skin blistering and tissue separation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.