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Mouse Collagen Type IV Alpha 1 (COL4a1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Collagen Type IV Alpha 1 (COL4a1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse COL4a1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Type IV collagen is the primary structural component of glomerular basement membranes (GBM), creating a 'chicken-wire' meshwork alongside laminins, proteoglycans, and entactin/nidogen. Arresten, derived from the C-terminal NC1 domain, inhibits angiogenesis and tumor formation, with the C-terminal half specifically exhibiting anti-angiogenic activity. It effectively hinders endothelial cell proliferation, migration, and tube formation. In mice, the COL4A1 gene is essential for supporting the normal function of multiple organ systems by maintaining basement membrane integrity and function. However, mutations in this gene can lead to basement membrane defects and associated diseases, such as vascular, kidney, eye, and neurological disorders.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.