Mouse Coenzyme Q10 (CoQ10) ELISA Kit-Competitive

Coenzyme Q10 plays a vital role as a cofactor in the mitochondrial electron transport chain and offers antioxidant properties that protect neurons from oxidative stress. Research indicates that Coenzyme Q10 markedly reduces striatal damage caused by 3-nitropropionic acid and extends survival in amyotrophic lateral sclerosis (ALS) mouse models. Furthermore, Coenzyme Q10 has been shown to enhance motor and cognitive functions in Parkinson's disease (PD) and Huntington's disease (HD) mouse models. In middle-aged mice, supplementation with Coenzyme Q10 can reactivate neuronal activity in the primary motor cortex, thereby improving motor function. It achieves this by enhancing NMDA receptor-dependent long-term potentiation (LTP), which increases the excitability of layer V neurons. As an antioxidant, Coenzyme Q10 works within the cell membrane, either by directly neutralizing free radicals or by regenerating other antioxidants like vitamin E and vitamin C.