Mouse Cocaine And Amphetamine Regulated Transcript (CART) ELISA Kit-Sandwich

The cocaine- and amphetamine-regulated transcript protein acts as a satiety factor, intricately linked with leptin and neuropeptide Y actions. This anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y, with regulation occurring in the hypothalamus. In mice, the expression of the Cartpt gene is influenced by multiple factors. For instance, in the midbrain dopamine region, its expression correlates with behavior following acute cocaine self-administration, indicating a role in addictive behavior. Additionally, in the mouse hypothalamus, the Cartpt gene is linked to dietary regulation, and its expression may influence neurohormone secretion, thereby indirectly impacting appetite and energy metabolism.