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Mouse Coagulation Factor XII (F12) ELISA Kit-Sandwich

Cat. No.EK5F622

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Coagulation Factor XII (F12) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse F12 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Coagulation Factor XII (F12).
Target Species Mouse
Species Reactivity Mouse
Detection Range 62.5-4000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Factor XII is a serum glycoprotein involved in initiating blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It cleaves prekallikrein to form kallikrein, which, in turn, cleaves Factor XII to alpha-factor XIIa, followed by trypsin cleaving it to beta-factor XIIa. Alpha-factor XIIa then activates factor XI to factor XIa. In mice, FXII has complex and diverse functions, playing crucial roles in thrombosis and inflammatory responses, with potential applications in anticoagulant therapy. However, its impact on normal hemostasis is relatively minor.

Target/Biomarker Mouse F12
Target Synonym FXII; HAF; Contact Factor; Hageman Factor
Gene ID 58992
UniProt ID Q80YC5

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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