This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Cluster of Differentiation 19 (CD19) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Cluster of Differentiation 19 (CD19) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CD19 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
B-lymphocyte antigen CD19 serves as a coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes, lowering the threshold for activating downstream signaling pathways and triggering B-cell responses to antigens. It activates pathways leading to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores. In mice, CD19 plays multiple roles, including regulating B cell development, activation, and differentiation, influencing humoral immunity and autoimmune responses, and interacting with the complement system and other molecules. Abnormal CD19 function is linked to various diseases; for example, in a systemic lupus erythematosus model, mice overexpressing CD19 exhibited high titers of autoantibodies and severe autoimmune reactions.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.