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Mouse Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Chemokine C-X3-C-Motif Ligand 1 (CX3CL1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CX3CL1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Fractalkine is a chemokine that serves as a ligand for CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1, playing a key role in regulating leukocyte adhesion and migration at the endothelium. It can activate integrins through both CX3CR1-dependent and independent mechanisms. In mice, Fractalkine (FKN) is primarily involved in interactions with its receptor, CX3CR1. Research indicates that Fractalkine is crucial in the central nervous system (CNS) by binding to CX3CR1, facilitating the chemotactic migration and activation of microglia. In mouse models, Fractalkine enhances intracellular calcium levels in microglia, an effect that can be inhibited by blocking the CX3CR1 receptor.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.