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Mouse Chemokine C-X-C-Motif Receptor 3 (CXCR3) ELISA Kit-Sandwich

Cat. No.EK5F842

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Chemokine C-X-C-Motif Receptor 3 (CXCR3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CXCR3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Chemokine C-X-C-Motif Receptor 3 (CXCR3).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

C-X-C chemokine receptor type 3 (CXCR3) acts as a receptor for the chemokines CXCL9, CXCL10, and CXCL11, mediating the proliferation, survival, and angiogenic activity of mesangial cells via a heterotrimeric G-protein signaling pathway. It is likely involved in promoting the cell chemotaxis response. In mice, the functions of CXCR3 are varied and complex, encompassing immune regulation, inflammatory response, tumor metastasis, tissue repair, and neuroprotection. In mouse models, CXCR3 facilitates the migration of effector T cells to sites of inflammation by interacting with its ligands CXCL9, CXCL10, and CXCL11, thereby contributing to the development of various inflammatory diseases, including rheumatoid arthritis and multiple sclerosis.

Target/Biomarker Mouse CXCR3
Target Synonym CD183; CKR-L2; CMKAR3; GPR9; IP10r; IP10-R; Mig-R; MigR; G Protein-Coupled Receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor
Gene ID 12766
UniProt ID O88410

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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