This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Cerebral Dopamine Neurotrophic Factor (CDNF) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Cerebral Dopamine Neurotrophic Factor (CDNF) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CDNF in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Cerebral dopamine neurotrophic factor (CDNF) is vital for supporting dopamine neurons, preventing their degeneration caused by 6-hydroxydopamine (6-OHDA). When administered following 6-OHDA lesioning, it restores dopaminergic function and averts further degeneration of dopaminergic neurons in the substantia nigra. CDNF demonstrates substantial neuroprotective effects in mice, particularly in Parkinson's disease models. Research has shown that CDNF can safeguard midbrain dopamine neurons from toxic damage induced by MPTP (1-methyl-4-pyridyl azo). For instance, CDNF injections have been found to enhance both horizontal and vertical motor behavior in mice and increase the count of dopamine-positive neurons in the striatum and substantia nigra.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.