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Mouse Cathepsin S (CTSS) ELISA Kit-Sandwich

Cat. No.EK5F585

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Cathepsin S (CTSS) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CTSS in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Cathepsin S (CTSS).
Target Species Mouse
Species Reactivity Mouse
Detection Range 31.25-2000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Cathepsin S is a thiol protease crucial for removing the invariant chain from MHC class II molecules and facilitating MHC class II antigen presentation. Its bond specificity is somewhat akin to that of cathepsin L. In mice, the function of cathepsin S (catS) primarily pertains to the immune response, especially in the degradation of the invariant chain (Ii) by antigen-presenting cells (APCs). Studies indicate that both catS and catL are involved in the later stages of Ii degradation. However, unlike catL, catS activity is significantly increased in macrophages (Mφs) stimulated by interferon-γ (IFN-γ), while catL has little effect under these conditions.

Target/Biomarker Mouse CTSS
Target Synonym CTS-S
Gene ID 13040
UniProt ID O70370

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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