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Mouse Cathepsin D (CTSD) ELISA Kit-Sandwich

Cat. No.EK5F635

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Cathepsin D (CTSD) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CTSD in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Cathepsin D (CTSD).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Cathepsin D is an acid protease involved in the breakdown of intracellular proteins. It contributes to APP processing by being cleaved and activated by ADAM30, leading to APP degradation. In mice, Cathepsin D has diverse roles, such as regulating cell apoptosis, promoting tissue repair, participating in immune regulation, and influencing disease progression. In a DSS-induced colitis model, heightened expression of Cathepsin D was linked to the apoptosis of intestinal epithelial cells and increased inflammation. In studies related to Alzheimer's disease (AD), Cathepsin D has been associated with the C-terminal cleavage of the Tau protein.

Target/Biomarker Mouse CTSD
Target Synonym CPSD; CLN10; Lysosomal Aspartyl Protease; Ceroid-Lipofuscinosis;Neuronal 10
Gene ID 13033
UniProt ID P18242

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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