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Mouse Caspase 12 (CASP12) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Caspase 12 (CASP12) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CASP12 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Caspase-12 exhibits significant anti-inflammatory function in mice. Studies have shown that Caspase-12 inhibits the production of inflammatory factors such as IL-1β and IL-18 by inhibiting the activity of Caspase-1, but does not affect the production of TNFα or IL-6. This mechanism makes Caspase-12 a "pseudo-inflammatory" caspase that functions similarly to CFLIP, reducing inflammatory responses by negatively regulating the activation of inflammatory caspases. Caspase-12 plays an important role in endoplasmic reticulum stress (ER stress)-induced apoptosis. It can specifically cleave procaspase-9, thereby initiating a caspase-9-dependent apoptotic cascade.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.