Mouse Carnitine Palmitoyltransferase 1A, Liver (CPT1A) ELISA Kit-Sandwich

The liver isoform of Carnitine O-palmitoyltransferase 1 facilitates the transfer of acyl groups from long-chain fatty acid-CoA conjugates to carnitine, which is crucial for transporting long-chain fatty acids into the mitochondria where they undergo beta-oxidation. This enzyme is vital for triglyceride metabolism in the liver and shows anti-apoptotic properties in the ALI mouse model, where its overexpression can markedly decrease lung cell apoptosis and mitigate inflammatory responses triggered by LPS. In older male mice, lacking CPT1A can enhance cognitive function, motor skills, and muscle mass, while reducing oxidative stress and inflammation. Additionally, CPT1A is involved in regulating energy balance and feeding behavior; its absence under conditions of food restriction impacts both energy metabolism and feeding habits in mice.