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Mouse Carboxypeptidase N1 (CPN1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Carboxypeptidase N1 (CPN1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CPN1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Carboxypeptidase N polypeptide 1 protects the body by inactivating potent vasoactive and inflammatory peptides with C-terminal Arg or Lys, such as kinins and anaphylatoxins, released into the circulation. CPN1 is a plasma zinc metalloproteinase known for its anti-inflammatory effects, as it cleaves bioactive peptides like the complement components C3a and C5a, which possess inflammatory activity. Research has demonstrated that the absence of CPN1 in mice increases their susceptibility to lethal anaphylactic shock. This heightened vulnerability is due to their inability to effectively degrade these inflammatory mediators, resulting in acute complement activation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.