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Mouse Carbonic Anhydrase IX (CA9) ELISA Kit-Sandwich

Cat. No.EK5F971

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Carbonic Anhydrase IX (CA9) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CA9 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Carbonic Anhydrase IX (CA9).
Target Species Mouse
Species Reactivity Mouse
Detection Range 1.57-100 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Carbonic anhydrase 9 (CAIX) facilitates the interconversion between carbon dioxide, water, and the dissociated ions of carbonic acid (bicarbonate and hydrogen ions). In mice, CAIX primarily regulates the differentiation and proliferation of gastric mucosa and is crucial for maintaining the gastrointestinal acid-base balance. It is highly expressed in the gastric mucosa, and its absence leads to abnormal differentiation and proliferation of gastric mucosal epithelial cells. Specifically, there is an increase in the number of gastric mucosal epithelial cells and mucus-secreting cells, along with a decrease in the number of chief cells. These changes are likely linked to CAIX's regulatory role in the differentiation of gastric mucosal epithelial cells.

Target/Biomarker Mouse CA9
Target Synonym CA-IX; CAIX; MN; pMW1; P54/58N; Carbonic Dehydratase; Renal cell carcinoma-associated antigen G250; RCC-Associated Protein G250; Carbonate dehydratase IX
Gene ID 230099
UniProt ID Q8VHB5

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Kallio, Heini et al. "Global transcriptional response to carbonic anhydrase IX deficiency in the mouse stomach." BMC genomics vol. 11 397. 23 Jun. 2010.
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