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Mouse Calcium Channel, Voltage Dependent, L-Type, Alpha 1F Subunit (CACNa1F) ELISA Kit-Sandwich

Cat. No.EK6F383

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Calcium Channel, Voltage Dependent, L-Type, Alpha 1F Subunit (CACNa1F) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CACNa1F in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Calcium Channel, Voltage Dependent, L-Type, Alpha 1F Subunit (CACNa1F).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Voltage-sensitive calcium channels (VSCCs) facilitate the entry of calcium ions into excitable cells and play a vital role in numerous calcium-dependent processes, such as muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. Mutations in the Cacna1f gene result in retinal dysfunction, marked by impaired formation of photoreceptor synapses, reduced retinal layer thickness, and abnormal distribution of retinal neurons. For instance, in the nob2 mouse model, complete loss of the Cacna1f gene causes disorganized outer retinal layers (OPL), diminished photoreceptor synapses, abnormal morphology of rod and bipolar cells, and irregular neuronal extensions in the outer nuclear layer.

Target/Biomarker Mouse CACNa1F
Target Synonym CORDX3; CSNB2; CSNB2A; CSNBX2; Cav1.4; JM8; JMC8; COD4; Voltage-gated calcium channel subunit alpha Cav1.4
UniProt ID Q9JIS7

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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