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Mouse Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D) ELISA Kit-Sandwich

Cat. No.EK6F382

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CACNa1D in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Voltage-sensitive calcium channels (VSCCs) facilitate the entry of calcium ions into excitable cells and are integral to various calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. In mouse models, the knockout or loss of function of the Cacna1d gene results in neurobehavioral abnormalities such as hyperactivity, reduced sociability, and impaired learning and memory. These traits mirror neurodevelopmental syndromes seen in human patients. Additionally, in mice, Cacna1d gene knockout leads to reduced insulin secretion and impaired glucose tolerance, highlighting the gene's important role in regulating blood glucose homeostasis.

Target/Biomarker Mouse CACNa1D
Target Synonym CACH3; CACN4; CACNL1A2; CCHL1A2; Cav1.3; Voltage-gated calcium channel subunit alpha Cav1.3; Calcium channel; L type; alpha-1 polypeptide; isoform 2
Gene ID 12289
UniProt ID Q99246

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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