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Mouse Cajal Interstitial Cells-Immortalized by SV40T Antigens
Product Overview
Cajal interstitial cells (CICs) are a type of specialized cell distributed in a network between the enteric nervous system terminals and smooth muscle cells in the digestive tract. The generation and maintenance of gastrointestinal motility result from the synergistic action of Cajal interstitial cells, the enteric nervous system, and smooth muscle cells. Interstitial cells can not only spontaneously generate rhythmic slow waves but also mediate signal regulation between the enteric nervous system and smooth muscle. Mouse Cajal Interstitial Cells-Immortalized by SV40T Antigens were immortalized through lentiviral transfection carrying the SV40 gene (these cells acquire puromycin resistance after transfection).
Specifications
Target Information
These cells are transformed and stably express the large T-antigen of the simian virus 40 (SV40T antigens) to immortalize the cells and extend their lifespan.
Shipping and Storage
This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.