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Mouse C1q And Tumor Necrosis Factor Related Protein 3 (C1QTNF3) ELISA Kit-Sandwich

Cat. No.EK6F599

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse C1q And Tumor Necrosis Factor Related Protein 3 (C1QTNF3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse C1QTNF3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse C1q And Tumor Necrosis Factor Related Protein 3 (C1QTNF3).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

C1qtnf3 is an anti-inflammatory secretory protein that functions by inhibiting the NF-κB signaling pathway. Research indicates that C1qtnf3 can suppress the production of inflammatory factors triggered by lipopolysaccharide (LPS) and preserve the integrity of articular cartilage in mouse models. In a mouse model of collagen-induced arthritis, the absence of C1qtnf3 worsens arthritis progression, while its overexpression mitigates the inflammatory response. Additionally, C1qtnf3 expression is significantly upregulated in obesity and tumor-associated peritoneal adipose tissue. It is primarily expressed by fibroblasts and influences adipose tissue remodeling by promoting the chemotaxis and polarization of macrophages.

Target/Biomarker Mouse C1QTNF3
Target Synonym CORS26; CTRP3; Corcs; Cors; Cartonectin; Collagenous repeat-containing sequence 26 kDa protein
Gene ID 81799
UniProt ID Q9ES30

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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