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Mouse C-X-C Motif Chemokine 17 (VCC1) ELISA Kit-Sandwich

Name: Mouse C-X-C Motif Chemokine 17 (VCC1) ELISA Kit-Sandwich
SKU: EK6F324
Rating: 5 (1 reviews)

Cat. No.EK6F324

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse C-X-C Motif Chemokine 17 (VCC1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse VCC1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse C-X-C Motif Chemokine 17 (VCC1).

Target Species Mouse

Species Reactivity Mouse

Detection Range 15.7-1000 pg/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

C-X-C motif chemokine 17 is a chemokine that serves as a chemoattractant for monocytes, macrophages, and dendritic cells, playing a role in angiogenesis and potentially in tumor development. CXCL17 is involved in the inflammatory response by attracting these specific immune cells. In CXCL17 knockout mice (CXCL17−/−), stimulation with lipopolysaccharide (LPS) revealed a significant defect in neutrophil recruitment, indicating CXCL17's crucial role in the early inflammatory response. Additionally, CXCL17 exhibits a broad spectrum of antimicrobial activity, capable of inhibiting the growth of bacteria and fungi, thus positioning it as a potential antimicrobial factor.

Target/Biomarker Mouse VCC1

Target Synonym CXCL17; SCYB17; DMC; Chemokine C-X-C-Motif Ligand 7; Dendritic cell and monocyte chemokine-like protein

Gene ID 232983

UniProt ID Q5UW37

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Giblin, Sean P et al. "CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signaling." Frontiers in immunology vol. 14 1254697. 24 Oct. 2023.