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Mouse Bruton's Tyrosine Kinase (Btk) ELISA Kit-Sandwich

Cat. No.EK5F853

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Bruton's Tyrosine Kinase (Btk) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse Btk in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Bruton's Tyrosine Kinase (Btk).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Tyrosine-protein kinase BTK is a non-receptor tyrosine kinase crucial for the development, differentiation, and signaling of B lymphocytes. When an antigen binds to the B-cell antigen receptor (BCR), it initiates signaling that leads to B-cell activation. BTK, a cytoplasmic tyrosine kinase belonging to the Tec family, is vital for B cell receptor (BCR) signaling. In mice, mutations in the BTK gene result in X-linked agammaglobulinemia (XID), characterized by halted B cell development, though B cells are still present. Beyond its role in B cell function, BTK is also important in the innate immune system of mice.

Target/Biomarker Mouse Btk
Target Synonym AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA; Bruton Agammaglobulinemia Tyrosine Kinase; B-cell progenitor kinase
Gene ID 12229
UniProt ID P35991

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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