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Mouse Breast Cancer Cell Line-4T1-OVA

Cat. No.CC8F88

Product TypeAnimal Cells and Cell Lines

Product Overview

4T1 is a 6-thioguanine resistant cell line selected from the 410.4 tumor, without mutagenic treatment. The tumor growth and metastatic spread of 4T1 cells in BALB/c mice closely resemble human breast cancer. This makes the tumor an animal model for stage IV human breast cancer. When injected into BALB/c mice, 4T1 spontaneously produces highly metastatic tumors. As the primary tumor grows in its original location, it also metastasizes to the lungs, liver, lymph nodes, and brain. 4T1-induced tumors can serve as both a post-operative model and a non-surgical model, because the tumors they induce spontaneously metastasize in both models with similar kinetics. Mouse Breast Cancer Cell Line-4T1-OVA are 4T1 cells infected with lentivirus and stably overexpress OVA.

Specifications

Cell Product Type Cell Line
Species Mouse
Cell Type Tumor Cell Line
Source Breast Cancer
Disease Breast Cancer
Growth Information Adherent; 37°C; 5%CO2
Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)
Formulation and Cell Culture Medium RPMI-1640 with 10% FBS
Physical State Frozen cells

Target Information

This cell line is a cell line stably overexpressing OVA obtained by infecting 4T1 cells with lentivirus.

Target/Biomarker OVAL
Target Synonym ovalbumin; OVAL; OVA; SERPINB14; allergen Gal d II; clade (ovalbumin); egg albumin; member 14; plakalbumin; serpin peptidase inhibitor
Gene ID 396058
UniProt ID P01012

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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