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Mouse Bone Marrow Macrophages-Immortalized by SV40T Antigens

Cat. No.CC7F219

Product TypeAnimal Cells and Cell Lines

Product Overview

Macrophages originate from monocytes and are a type of immune cell with diverse functions. They belong to a non-proliferating cell population, making them difficult to culture long-term. Macrophages play extensive biological roles in phagocytosing and clearing foreign bodies and senescent/dead cells, secreting bioactive substances, regulating hematopoiesis, and participating in immune responses. They are a critical immune effector cell type in the body, ensuring the maintenance of homeostasis and tissue defense. Mouse Bone Marrow Macrophages-Immortalized by SV40T Antigens were transduced with the SV40 gene via lentiviral transfection (these cells become puromycin-resistant after transfection).

Specifications

Cell Product Type Cell Line
Species Mouse
Cell Type Immortalized Cell Line
Source Bone Marrow
Growth Information Adherent; 37°C; 5%CO2
Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)
Physical State Frozen cells

Target Information

These cells are transformed and stably express the large T-antigen of the simian virus 40 (SV40T antigens) to immortalize the cells and extend their lifespan.

Target/Biomarker SV40T antigens
Target Synonym large T antigen [ Simian virus 40 ]
Gene ID 1489531

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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