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Mouse Bone Marrow Macrophages-Immortalized by SV40T Antigens
Product Overview
Macrophages originate from monocytes and are a type of immune cell with diverse functions. They belong to a non-proliferating cell population, making them difficult to culture long-term. Macrophages play extensive biological roles in phagocytosing and clearing foreign bodies and senescent/dead cells, secreting bioactive substances, regulating hematopoiesis, and participating in immune responses. They are a critical immune effector cell type in the body, ensuring the maintenance of homeostasis and tissue defense. Mouse Bone Marrow Macrophages-Immortalized by SV40T Antigens were transduced with the SV40 gene via lentiviral transfection (these cells become puromycin-resistant after transfection).
Specifications
Target Information
These cells are transformed and stably express the large T-antigen of the simian virus 40 (SV40T antigens) to immortalize the cells and extend their lifespan.
Shipping and Storage
This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.