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Mouse B-Cell CLL/Lymphoma 9 (Bcl9) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse B-Cell CLL/Lymphoma 9 (Bcl9) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse Bcl9 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
B-cell CLL/lymphoma 9-like protein (Bcl9l) is a transcriptional regulator that functions as an activator, enhancing beta-catenin's transcriptional activity and playing a crucial role in tumorigenesis. It amplifies the neoplastic transforming activity of CTNNB1. In mice, Bcl9l serves several important roles, including the regulation of the Wnt/β-catenin signaling pathway, the promotion of tumorigenesis and immune response, and involvement in tissue development and embryonic survival. In the context of mouse retinal development, Bcl9l operates in a Pax6-dependent but β-catenin-independent manner. In cases of colorectal cancer, the loss of Bcl9l hinders tumor initiation and progression, and prolongs survival in mice with a liver-specific β-catenin mutation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.