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Mouse B-Cell Activating Factor (BAFF/CD257) ELISA Kit-Sandwich

Cat. No.EK5F601

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse B-Cell Activating Factor (BAFF/CD257) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse BAFF/CD257 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse B-Cell Activating Factor (BAFF/CD257).
Target Species Mouse
Species Reactivity Mouse
Detection Range 12.5-800 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Tumor necrosis factor ligand superfamily member 13B, also known as B-cell-activating factor (BAFF), is a cytokine that binds to the receptors TNFRSF13B/TACI and TNFRSF17/BCMA. The cytokine TNFSF13/APRIL also binds to these two receptors, creating a dual ligand-receptor pathway that plays a crucial role in stimulating B- and T-cell functions and regulating humoral immunity. Additionally, a third receptor specific to B-cells, the BAFF-receptor (BAFFR/BR3), supports the survival of mature B-cells and enhances the B-cell response. In mice, TNFSF13B is involved in various biological processes, primarily focusing on B-cell activation, immune regulation, and its involvement in multiple diseases, including autoimmune disorders, tumors, and osteoporosis.

Target/Biomarker Mouse BAFF/CD257
Target Synonym CD257; TNFSF13B; BLYS; TALL1; THANK; TNFSF20; ZTNF4; B lymphocyte stimulator; Tumor Necrosis Factor Ligand Superfamily Member 13B; Dendritic cell-derived TNF-like; BAFF
Gene ID 24099
UniProt ID Q9WU72

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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