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Mouse Ataxia Telangiectasia Mutated (ATM) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Ataxia Telangiectasia Mutated (ATM) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ATM in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Serine-protein kinase ATM is a serine/threonine protein kinase that initiates checkpoint signaling in response to DNA double-strand breaks (DSBs), apoptosis, and genotoxic stresses like ionizing ultraviolet A light (UVA), functioning as a DNA damage sensor. This kinase is integral to the DNA damage response in mammals, playing a pivotal role in biological processes such as DNA repair, cell cycle regulation, immune response, and tumor development. In mice, mutations in the ATM gene can result in various physiological and developmental issues, including growth retardation, chromosome fragmentation, meiotic failure, immune deficiencies, and the development of thymic lymphoma.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.