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Mouse Aquaporin 4 (AQP4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Aquaporin 4 (AQP4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse AQP4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Aquaporin-4 (AQP4) is crucial for maintaining brain water homeostasis and facilitating glymphatic solute transport, being essential for the normal rate of water exchange across the blood-brain barrier. In mice, AQP4 is involved in various physiological and pathological processes, including brain edema, blood-brain barrier integrity, neuronal activity, and sensory function. Its role has been highlighted in various disease models. For instance, in multiple sclerosis models, AQP4 expression is linked to inflammatory responses and tissue damage, while in neurodegenerative diseases, abnormal AQP4 expression may be related to the accumulation of amyloid β protein.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Ratelade, Julien et al. "Intravenous neuromyelitis optica autoantibody in mice targets aquaporin-4 in peripheral organs and area postrema." PloS one vol. 6,11 (2011): e27412.