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Mouse Aquaporin-2 (AQP2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Aquaporin-2 (AQP2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse AQP2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Aquaporin-2 forms a water-specific channel that endows the plasma membranes of renal collecting ducts with high water permeability, allowing water to move along an osmotic gradient. In mice, aquaporin-2 (AQP2) is chiefly responsible for water reabsorption and urine concentration in the kidney. AQP2, regulated by the antidiuretic hormone (ADH, also known as vasopressin), is primarily expressed in the epithelial membrane of the principal cells of the renal collecting ducts. Proper functioning of AQP2 is crucial for maintaining fluid balance. Mice with the AQP2-F204V mutation can survive into adulthood; however, their AQP2 protein is retained in the endoplasmic reticulum instead of reaching the cell membrane, leading to a defect in urine concentration.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.