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Mouse Apolipoprotein C3 (APOC3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Apolipoprotein C3 (APOC3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse APOC3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Apolipoprotein C-III is a component found in triglyceride-rich very low-density lipoproteins (VLDL) and high-density lipoproteins (HDL) in plasma, playing a complex role in triglyceride homeostasis. Intracellularly, it facilitates the assembly and secretion of hepatic very low-density lipoprotein 1 (VLDL1), while extracellularly, it reduces the hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). In mice, the role of ApoC3 is primarily observed in its impact on lipid metabolism, including the inhibition of triglyceride hydrolysis, promotion of insulin resistance and obesity, and its link to cardiovascular disease and liver issues. Additionally, ApoC3 is involved in regulating HDL function and may influence systemic metabolism by affecting fatty acid oxidation and energy metabolism. For instance, in obese mice, the upregulation of ApoC3 is associated with increased metabolic activity in adipose tissue.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.