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Mouse Apolipoprotein C3 (APOC3) ELISA Kit-Sandwich

Cat. No.EK5F655

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Apolipoprotein C3 (APOC3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse APOC3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Apolipoprotein C3 (APOC3).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.8-50 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Apolipoprotein C-III is a component found in triglyceride-rich very low-density lipoproteins (VLDL) and high-density lipoproteins (HDL) in plasma, playing a complex role in triglyceride homeostasis. Intracellularly, it facilitates the assembly and secretion of hepatic very low-density lipoprotein 1 (VLDL1), while extracellularly, it reduces the hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). In mice, the role of ApoC3 is primarily observed in its impact on lipid metabolism, including the inhibition of triglyceride hydrolysis, promotion of insulin resistance and obesity, and its link to cardiovascular disease and liver issues. Additionally, ApoC3 is involved in regulating HDL function and may influence systemic metabolism by affecting fatty acid oxidation and energy metabolism. For instance, in obese mice, the upregulation of ApoC3 is associated with increased metabolic activity in adipose tissue.

Target/Biomarker Mouse APOC3
Target Synonym Apo-C3; APOCIII; APOC-III
Gene ID 11814
UniProt ID P33622

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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