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Mouse Anti-Rat Transforming Growth Factor Beta 2 (TGFb2) Monoclonal Antibody

Cat. No.VD2N281

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for rat transforming growth factor beta 2. It is affinity purified by protein A and protein G . It can be applied to WB, IHC, ICC and IP assays of rat transforming growth factor beta 2.

Specifications

Application WB; IHC; ICC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone A25N10
Host Mouse
Target Species Rat
Species Reactivity Rat
Specificity Rat Transforming Growth Factor Beta 2
Isotype IgG
Immunogen Recombinant protein of rat transforming growth factor beta 2
Purification Purified by Protein A and Protein G
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Rat TGFb2 is a member of the TGF-β superfamily, characterized by a cysteine knot structure. It is a glycosylated protein that controls key physiological processes, including cell migration, proliferation, and differentiation. TGFb2 signals through a heteromeric receptor complex consisting of TGF-β receptor type I (TβR-I) and type II (TβR-II), mediating downstream effects via SMAD proteins. It is widely expressed in various tissues, such as cartilage, bone, muscle, and the nervous system. TGFb2 also plays a role in immune modulation and embryonic development.

Target Rat Transforming Growth Factor Beta 2
Target Synonym TGF-B2; TGF-Beta2; G-TSF; LAP; Cetermin; Polyergin; Latency-associated peptide; BSC-1 cell growth inhibitor; Glioblastoma-derived T-cell suppressor factor
Gene ID 81810
UniProt ID Q07257

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Wolf, Yehuda G., et al. "Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model." The Journal of clinical investigation 93.3 (1994): 1172-1178.
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