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Mouse Anti-Rat Epidermal Growth Factor (EGF) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for rat epidermal growth factor. It is affinity purified by protein A and protein G . It can be applied to WB, IHC, ICC and IP assays of rat epidermal growth factor.
Specifications
Target Information
Rat Epidermal Growth Factor (EGF) is a small, 6.2 kDa globular protein that exerts its actions by binding to the EGF Receptor (EGFR), a 170 kDa protein kinase. Activation of EGFR initiates diverse cellular pathways, including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCγ-PKC, and STAT signaling modules. EGF acts as a potent mitogenic factor, promoting cell proliferation and differentiation. It is widely expressed in various tissues, including the kidney, cerebrum, prostate, and salivary glands.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Schreiber, Alain B., et al. "Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies." Journal of Biological Chemistry 258.2 (1983): 846-853.