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Mouse Anti-Mouse Granzyme K (GZMK) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for mouse granzyme K. It is purified by protein A and protein G. It can be applied to WB, IHC, ICC and IP assays of mouse granzyme K.
Specifications
Target Information
Mouse granzyme K (GzmK) is a 32-kDa serine protease predominantly expressed in mouse cytotoxic lymphocytes-including natural killer (NK) cells, NKT cells, and subsets of CD8⁺ T cells. It is stored in cytoplasmic granules and released upon immune activation, mediating target cell apoptosis via cleavage of pro-apoptotic substrates. Beyond cytotoxicity, it modulates inflammatory responses by regulating cytokine production and immune cell recruitment. Ubiquitous in mouse lymphoid tissues (spleen, lymph nodes) and inflamed sites, it supports anti-viral, anti-tumor, and autoimmune responses. As a key effector molecule of cytotoxic lymphocytes, mouse GzmK is a critical target for studying immune-mediated cell death, infectious diseases, and tumor immunology.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.