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Mouse Anti-Canine Sarcalumenin Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine Sarcalumenin. It can be applied to WB, ICC/IF and IHC assays of canine Sarcalumenin.
Specifications
Target Information
Canine sarcalumenin is a 160 kDa calcium-binding glycoprotein that resides in the sarcoplasmic reticulum (SR), playing a crucial role in calcium transport and sequestration within muscle cells. It is found in the longitudinal SR and co-localizes with calcium-ATPase, suggesting its involvement in the regulation of calcium reuptake into the SR. Sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein, which co-localizes with sarcalumenin and may contribute to its function. This protein's role in calcium homeostasis is essential for muscle contraction and relaxation, making it a significant target for understanding and potentially managing conditions related to muscle dysfunction in dogs.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.