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Mouse Anti-Canine Regulated on Activation in Normal T-Cell Expressed and Secreted (RANTES) Monoclonal Antibody

Cat. No.VD2N195

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for canine regulated on activation in normal T-cell expressed and secreted. It is affinity purified by protein A and protein G . It can be applied to WB, IHC, ICC and IP assays of canine regulated on activation in normal T-cell expressed and secreted.

Specifications

Application WB; IHC; ICC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone A19N7
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Regulated on Activation in Normal T-Cell Expressed and Secreted
Isotype IgG2
Immunogen Recombinant protein of canine regulated on activation in normal T-cell expressed and secreted
Purification Purified by Protein A and Protein G
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Canine Regulated on Activation, Normal T Cell Expressed and Secreted (RANTES), also known as CCL5, is a chemokine produced by activated T cells and other immune cells. It plays a crucial role in recruiting leukocytes, particularly monocytes, T cells, and eosinophils, to sites of inflammation. RANTES acts through the CCR1, CCR3, and CCR5 receptors, mediating various immune responses. This chemokine is involved in immune regulation and has been implicated in the pathogenesis of inflammatory and autoimmune diseases in dogs.

Target Canine Regulated on Activation in Normal T-Cell Expressed and Secreted
Target Synonym CCL5; SCYA5; SISd; EoCP; Chemokine C-C-Motif Ligand 5; Eosinophil Chemotactic Cytokine; T-cell Specific Protein p288; Small Inducible Cytokine Subfamily A(Cys-Cys)Member 5
Gene ID 403522
UniProt ID Q8HYS0

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Silva, José Eduardo dos Santos, et al. "Increased CCL-5 (RANTES) gene expression in the choroid plexus of dogs with canine leishmaniosis." Animals 13.13 (2023): 2060.
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